{
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  "Package": "imputeLCMD",
  "Type": "Package",
  "Title": "A Collection of Methods for Left-Censored Missing Data\nImputation",
  "Version": "2.1",
  "Date": "2022-06-09",
  "Authors@R": "c(\nperson(\"Cosmin\", \"Lazar\", email = \"vcosminlazar@gmail.com\", role = c(\"aut\")),\nperson(\"Thomas\", \"Burger\", email = \"thomas.burger@cea.fr\", role = c(\"aut\")),\nperson(\"Samuel\", \"Wieczorek\", email = \"samuel.wieczorek@cea.fr\", role = c(\"cre\", \"ctb\"))\n)",
  "Maintainer": "Samuel Wieczorek <samuel.wieczorek@cea.fr>",
  "Description": "A collection of functions for left-censored missing data\nimputation. Left-censoring is a special case of missing not at\nrandom (MNAR) mechanism that generates non-responses in\nproteomics experiments. The package also contains functions to\nartificially generate peptide/protein expression data\n(log-transformed) as random draws from a multivariate Gaussian\ndistribution as well as a function to generate missing data\n(both randomly and non-randomly). For comparison reasons, the\npackage also contains several wrapper functions for the\nimputation of non-responses that are missing at random. * New\nfunctionality has been added: a hybrid method that allows the\nimputation of missing values in a more complex scenario where\nthe missing data are both MAR and MNAR.",
  "License": "GPL (>= 2)",
  "Packaged": {
    "Date": "2026-05-16 08:36:10 UTC",
    "User": "root"
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  "NeedsCompilation": "no",
  "RoxygenNote": "7.2.0",
  "Encoding": "UTF-8",
  "Author": "Cosmin Lazar [aut], Thomas Burger [aut], Samuel Wieczorek [cre,\nctb]",
  "Repository": "https://samwieczorek.r-universe.dev",
  "Date/Publication": "2022-06-10 10:50:02 UTC",
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  "_published": "2026-06-02T18:15:05.230Z",
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  "_stars": 3,
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      "date": "2015-01-19"
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    "impute.MAR.MNAR",
    "impute.MinDet",
    "impute.MinProb",
    "impute.QRILC",
    "impute.wrapper.KNN",
    "impute.wrapper.MLE",
    "impute.wrapper.SVD",
    "impute.ZERO",
    "insertMVs",
    "model.Selector",
    "pep2prot"
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      "title": "Dataset PXD000022 from ProteomeXchange.",
      "object": "intensity_PXD000022",
      "file": "intensity_PXD000022.rda",
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        "Intensity.MB.2",
        "Intensity.MB.3",
        "Intensity.MT.1",
        "Intensity.MT.2",
        "Intensity.MT.3"
      ],
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      "table": true,
      "tojson": true
    },
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      "name": "intensity_PXD000052",
      "title": "Dataset PXD000052 from ProteomeXchange.",
      "object": "intensity_PXD000052",
      "file": "intensity_PXD000052.rda",
      "class": [
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      "fields": [
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        "iBAQ.stSLP_activ1",
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        "iBAQ.stSLP_activ3",
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        "iBAQ.stSLP_rest1",
        "iBAQ.stSLP_rest2",
        "iBAQ.stSLP_rest3",
        "iBAQ.stSLP_rest4",
        "iBAQ.WT_activ1",
        "iBAQ.WT_activ2",
        "iBAQ.WT_activ3",
        "iBAQ.WT_activ4",
        "iBAQ.WT_rest1",
        "iBAQ.WT_rest2",
        "iBAQ.WT_rest3",
        "iBAQ.WT_rest4"
      ],
      "rows": 1991,
      "table": true,
      "tojson": true
    },
    {
      "name": "intensity_PXD000438",
      "title": "Dataset PXD000438 from ProteomeXchange.",
      "object": "intensity_PXD000438",
      "file": "intensity_PXD000438.rda",
      "class": [
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      "fields": [
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        "Intensity.092.2",
        "Intensity.092.3",
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        "Intensity.441.2",
        "Intensity.441.3",
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        "Intensity.561.2",
        "Intensity.561.3",
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        "Intensity.691.2",
        "Intensity.691.3"
      ],
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      "table": true,
      "tojson": true
    },
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      "name": "intensity_PXD000501",
      "title": "Dataset PXD000501 from ProteomeXchange.",
      "object": "intensity_PXD000501",
      "file": "intensity_PXD000501.rda",
      "class": [
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        "iBAQ.secretome_set1_tech1",
        "iBAQ.secretome_set1_tech2",
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      "tojson": true
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      "topics": [
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      "title": "imputation under MAR/MCAR hypothesis",
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      ]
    },
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      "topics": [
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      "topics": [
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      "topics": [
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